How long does it take an antibiotic to exit your body once you stop taking it? I've been on Minocycline for my acne for a little under a month. My doctor increased me to 100MG's daily my last visit and for about four days now I've been dealing with this reflux crap, which is a couple days after I increased my Minocycline. So I've not taken three doses of my Minocycline hoping that this was the cause of the reflux, and I'm praying the reflux will go away after I stop taking this medicine. So, does anyone know when this medication will have fully exited my system? I feel so crappy. This stuff is coming high into my throat and I feel all nauseous from it. I'll probably end up ving from it because it's getting horrible. Rolaids are helping somewhat but not too much. Anyways, hopefully someone can answer this question. Thanks!